Optical Spectroscopy and Imaging for Disease Diagnosis

Research in our laboratory promotes better diagnosis, treatment, and prevention of human diseases through advancements in biophotonics technology – a field at the interface of physical sciences, engineering, biology, and medicine. Our projects target research for the development of optical spectroscopy and imaging techniques for medical diagnostics, integration of these techniques in multimodal tissue diagnostic platforms including optical coherence tomography, Raman spectroscopy, and high-frequency ultrasound technologies, and clinical validation of these technologies. We study the relationship between tissue pathology and measured optical signals. Our studies are conducted in close collaboration with clinical departments (surgery, neurosurgery, otolaryngology, cardiology, and pathology). Our work is supported by several major National Institutes of Health research grants.